Silence is a comic about music and the power it has to hold everything together when the world seems to be falling apart. The story takes place in the music town of Anthem, whose male population continues to dwindle as ships go missing at sea during routine shipping runs.
 
 The South Seas Capital Company holds Anthem in a death grip of debt, and many of its employees struggle to keep their houses from being repossessed by the bank. 
 
 Johanna Jones, a runaway from the town of Anthem receives a letter from the SSCC informing her that her father has gone missing after The September, the ship he was aboard, failed to return on time. They plan on repossessing her childhood home and allow her several days to collect any important belongings. Johanna reluctantly returns home to try to put together an expedition to search for The September’s whereabouts. 
 
Along with her best friend, a washed up elderly ex-punk rocker, an on again off again addict, she sets off on a yellow submarine called the Heart of Gold for Hades’ Hexagon, a mysterious area where ships keep disappearing.